A Love Letter to Comfort: Mastering the Spicy Southern Cheesy Chicken Spaghetti Casserole
This Spicy Southern Cheesy Chicken Spaghetti Casserole is creamy, cheesy, and full of Southern comfort. Tender chicken, al dente spaghetti, and zesty spices are layered with cheese for a dish that’s perfect for family dinners or cozy gatherings. Ready in under an hour, it’s a one-dish meal everyone will love!
Ingredients
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3–4 boneless, skinless chicken breasts (about 1.5 lbs)
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8 oz spaghetti
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2 cups shredded sharp cheddar cheese
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1 cup fresh bell peppers, chopped
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1 can (10.5 oz) cream of chicken soup
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1 tsp paprika
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½ tsp cayenne pepper
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1 tsp garlic powder
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¼ cup green onions, sliced (for garnish)
Instructions
1. Prep the Oven and Casserole Dish
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Preheat oven to 350°F (175°C).
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Grease a large casserole dish with butter or cooking spray.
2. Cook the Chicken
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In a large pot or skillet over medium heat, cook chicken 6–7 minutes per side until golden and fully cooked.
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Remove chicken and shred or chop into bite-sized pieces.
3. Cook the Spaghetti
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Boil salted water and cook spaghetti until al dente (8–10 minutes).
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Drain and set aside.
4. Combine Ingredients
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In a large bowl, mix together:
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Shredded chicken
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Cooked spaghetti
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Cream of chicken soup
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Chopped bell peppers
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Paprika, cayenne, garlic powder
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Half of the cheddar cheese
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5. Assemble the Casserole
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Transfer mixture into the greased casserole dish.
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Top with the remaining cheddar cheese.
6. Bake
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Bake 25–30 minutes until bubbly and golden brown.
7. Serve
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Let casserole rest 5 minutes before serving.
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Garnish with sliced green onions and enjoy!
Notes
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Cook spaghetti al dente: It will absorb flavors without getting mushy.
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Customize the spice: Adjust cayenne pepper to your heat preference.
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Add extra veggies: Mushrooms, zucchini, or corn work well.
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Make ahead: Assemble the casserole the night before and refrigerate; bake before serving.